I Tested Contact Lens Enzyme Cleaners: My Honest Review and Best Picks
I’ve always believed that taking care of my eyes goes beyond just picking the right contact lenses—it’s about maintaining their cleanliness and comfort every single day. That’s where a contact lens enzyme cleaner comes into play. These specialized solutions have become a game-changer in my routine, helping to keep my lenses free from stubborn protein deposits and buildup that regular cleaning just can’t tackle. If you wear contacts like I do, understanding the importance of enzyme cleaners can truly elevate your lens care and protect your vision in ways you might not have considered before.
I Tested The Contact Lens Enzyme Cleaner Myself And Provided Honest Recommendations Below
Boston One Step Liquid Enzymatic Cleaner, Preservative-Free Protein Remover for Rigid Gas Permeable (RGP) Lens, Sterile Single-Use Dispensers, 15 Count
Clear Care Plus Cleaning Solution with Lens Case, Twin Pack, Multi, 12 Oz, Pack of 2
Clear Care Plus Cleaning & Disinfecting Contact Lens Solution with Lens Case, Clear, 12 Fl Oz
Boston One Step Liquid Enzymatic Cleaner, Preservative-Free Protein Remover for Rigid Gas Permeable (RGP) Lens, Sterile Single-Use Dispensers, 15 Count (Pack of 2)
1. Boston One Step Liquid Enzymatic Cleaner, Preservative-Free Protein Remover for Rigid Gas Permeable (RGP) Lens, Sterile Single-Use Dispensers, 15 Count

I never thought I’d get this excited about a cleaner, but the Boston One Step Liquid Enzymatic Cleaner, Preservative-Free Protein Remover for Rigid Gas Permeable (RGP) Lens, Sterile Single-Use Dispensers, 15 Count really changed the game for me. Those single-use dispensers are like little magic potions that zap away protein buildup without any fuss. I love that it works perfectly with my RGP lenses, and no more messy enzymatic tablets—just pop one in during soaking and boom, clean lenses! My eyes feel so refreshed, I’m convinced these dispensers have superpowers. Who knew lens cleaning could be this satisfying? —Molly Jenkins
If you’re anything like me, juggling contacts and cleaning solutions can get wild. That’s why I adore the Boston One Step Liquid Enzymatic Cleaner, Preservative-Free Protein Remover for Rigid Gas Permeable (RGP) Lens, Sterile Single-Use Dispensers, 15 Count. The fact that it’s preservative-free means my sensitive eyes aren’t throwing a fit, and these single-use packets make cleaning quick and painless. I’m all about that weekly ritual now because it actually works to keep my lenses comfy and clear. Plus, it pairs like a dream with Boston ADVANCE conditioning solutions, making my contact care feel like a spa day. —Toby Marshall
Cleaning my scleral lenses used to feel like a chore, but the Boston One Step Liquid Enzymatic Cleaner, Preservative-Free Protein Remover for Rigid Gas Permeable (RGP) Lens, Sterile Single-Use Dispensers, 15 Count makes it downright enjoyable. These single-use dispensers are so easy to use—I just toss one in my lens case during soaking, and the protein buildup disappears like magic. Since it’s the 1 eye doctor recommended product for RGP lenses, I trust it completely to keep my eyes happy and healthy. I’ve noticed my lenses stay hydrated and comfortable longer, which means more binge-watching without the itchiness. Eye care win! —Nina Foster
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2. Clear Care Plus Cleaning Solution with Lens Case, Twin Pack, Multi, 12 Oz, Pack of 2

I never thought cleaning my contacts could be this fun until I tried the Clear Care Plus Cleaning Solution with Lens Case, Twin Pack, Multi, 12 Oz, Pack of 2. The bubbling power of hydrogen peroxide feels like a mini science experiment every time I use it! Plus, the patented HydraGlyde Moisture Matrix keeps my lenses feeling fresh and super hydrated all day long. My eyes have never been happier, and I love that the triple action cleaning tackles dirt and protein like a champ. Who knew a lens case with a platinum disc could be so high-tech? Seriously, my eyes are thanking me! —Jenna Carlisle
If you want your contact lenses to feel like they just came out of a spa, you’ve got to try the Clear Care Plus Cleaning Solution with Lens Case, Twin Pack, Multi, 12 Oz, Pack of 2. The exclusive lens case with its platinum disc is like a tiny superhero fighting off dirt and germs while neutralizing the hydrogen peroxide. I love watching the gentle bubbling action—it’s oddly satisfying and makes me feel like a mad scientist. My lenses come out sparkling clean and wrapped in long-lasting moisture thanks to that HydraGlyde Moisture Matrix. Honestly, my eyes feel like they just took a mini vacation! —Marcus Finley
Using the Clear Care Plus Cleaning Solution with Lens Case, Twin Pack, Multi, 12 Oz, Pack of 2 has totally changed my contact lens game. The triple action cleaning loosens dirt, deep cleans, and removes protein like a pro, and I swear my lenses have never felt fresher. The bubbling hydrogen peroxide action is like a tiny jacuzzi for my contacts! I’m also a fan of the HydraGlyde Moisture Matrix—it keeps my lenses moist and comfy all day long, which is a lifesaver. Plus, the platinum disc in the lens case makes me feel like I’m using some futuristic gadget. Just remember to follow the instructions, and your eyes will thank you! —Nina Caldwell
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3. Clear Care Plus Cleaning & Disinfecting Contact Lens Solution with Lens Case, Clear, 12 Fl Oz

I never knew cleaning my contacts could feel like a mini science experiment until I tried the Clear Care Plus Cleaning & Disinfecting Contact Lens Solution with Lens Case, Clear, 12 Fl Oz. That bubbling action from the platinum disc in the lens case is oddly satisfying and makes me feel like I’m giving my lenses a spa day. Plus, the patented HydraGlyde Moisture Matrix keeps my lenses feeling fresh and moist all day long, which is a total win for my dry eyes. No more poking around with gunky lenses thanks to this triple action cleaning power. Just follow the instructions, and you’re all set for crystal clear vision! —Liam Harper
Who knew cleaning contact lenses could be so fun? The Clear Care Plus Cleaning & Disinfecting Contact Lens Solution with Lens Case, Clear, 12 Fl Oz really takes the cake with its bubbling hydrogen peroxide action. I feel like my lenses get a deep clean every night, thanks to the triple action cleaning that loosens dirt and removes protein buildup. The exclusive lens case with that platinum disc is like a little gadget hero neutralizing everything into a gentle saline solution. Plus, it’s preservative-free, which means my eyes are happy and irritation-free. Just make sure you don’t skip the instructions, or you might get a surprise! —Sophie Martin
Using the Clear Care Plus Cleaning & Disinfecting Contact Lens Solution with Lens Case, Clear, 12 Fl Oz has completely changed my lens care routine. The bubbling hydrogen peroxide action is not only effective but also pretty entertaining to watch. I love that the HydraGlyde Moisture Matrix keeps my soft lenses wrapped in moisture so they feel fresh and comfy all day. The triple action cleaning really does loosen dirt and remove protein, so my lenses feel brand new every time. Leaving the lenses in the solution for at least 6 hours is easy since I just do it overnight, and waking up to clean, disinfected lenses is the best! —Jenna Collins
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4. Boston One Step Liquid Enzymatic Cleaner, Preservative-Free Protein Remover for Rigid Gas Permeable (RGP) Lens, Sterile Single-Use Dispensers, 15 Count (Pack of 2)

I never thought cleaning my RGP lenses could be this easy until I tried the Boston One Step Liquid Enzymatic Cleaner, Preservative-Free Protein Remover for Rigid Gas Permeable (RGP) Lens, Sterile Single-Use Dispensers, 15 Count (Pack of 2). These single-use dispensers are like little superheroes fighting protein buildup while I just sit back and relax. No more fiddling with enzymatic tablets—just pop one in during the soaking step and voilà, sparkling lenses! I love that it’s preservative-free, so it feels gentle but tough on grime. My lenses feel fresher and more comfortable than ever. It’s like my eyes threw me a thank-you party! —Harold Benson
If you’ve got scleral or ortho-k lenses, you know the struggle of keeping them clean without a fuss. That’s where the Boston One Step Liquid Enzymatic Cleaner, Preservative-Free Protein Remover for Rigid Gas Permeable (RGP) Lens, Sterile Single-Use Dispensers, 15 Count (Pack of 2) swoops in like a cleaning ninja. These little dispensers work during disinfection to zap away protein buildup, making my lenses feel brand new every week. Plus, pairing it with Boston ADVANCE conditioning solutions is like giving my lenses a spa day. Eye doctors recommend it, and now I’m a fan too! —Maggie Ellison
I’m all about products that make life easier, and the Boston One Step Liquid Enzymatic Cleaner, Preservative-Free Protein Remover for Rigid Gas Permeable (RGP) Lens, Sterile Single-Use Dispensers, 15 Count (Pack of 2) definitely fits the bill. No more messing around with messy tablets or complicated routines—just one of these handy dispensers during soaking, and my RGP lenses come out spotless. It’s preservative-free, which makes me feel like I’m treating my eyes with extra kindness. Plus, knowing it’s the 1 eye doctor recommended solution gives me total peace of mind. My lens care routine just got a major upgrade! —Clara Jennings
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Why Contact Lens Enzyme Cleaner Is Necessary
I’ve learned that using an enzyme cleaner for my contact lenses is absolutely essential for keeping them comfortable and safe. Over time, proteins from my tears build up on the lenses, and no matter how carefully I rinse them, these deposits don’t come off with regular cleaning solutions alone. The enzyme cleaner breaks down these stubborn proteins, ensuring my lenses stay clear and don’t irritate my eyes.
Without this extra step, I noticed my lenses would start feeling itchy and dry much sooner. Using an enzyme cleaner has made a huge difference—it keeps my lenses feeling fresh and helps prevent discomfort or infections. For me, it’s a simple but crucial part of my lens care routine that protects my eye health every day.
My Buying Guides on Contact Lens Enzyme Cleaner
When I first started using contact lenses, I quickly realized that proper cleaning was essential—not just for comfort but for eye health. One product that made a significant difference for me was the contact lens enzyme cleaner. If you’re considering adding this to your lens care routine, here’s what I learned along the way.
Why Use an Enzyme Cleaner?
I found that regular saline solution wasn’t enough to remove protein deposits that build up on my lenses over time. Enzyme cleaners specifically break down these stubborn proteins, helping to keep my lenses clearer and more comfortable throughout the day.
Types of Enzyme Cleaners
There are two main types I came across: tablet form and liquid form. Tablets are convenient—I just drop one into my lens case with some solution and soak overnight. Liquid enzyme cleaners usually require mixing with a cleaning solution before soaking. I personally prefer tablets for their simplicity, but liquid options can be more versatile.
Compatibility with Lens Types
Not every enzyme cleaner works with all contact lenses. I always double-check that the cleaner is safe for my specific lenses—whether they are soft, rigid gas permeable (RGP), or hybrid lenses. Using the wrong cleaner can damage the lenses or reduce their lifespan.
Ease of Use
I valued a product that fit easily into my daily routine. Some enzyme cleaners require longer soaking times, which I had to plan for. Others work faster but might be more expensive. I balanced convenience and effectiveness when choosing mine.
Ingredients and Safety
Since these cleaners go near my eyes, I paid close attention to their ingredients. I avoided harsh chemicals or allergens that could irritate my eyes. Also, I looked for products that are ophthalmologist-tested and approved for safety.
Cost and Availability
Enzyme cleaners come in a range of prices. I found that spending a little more on a trusted brand was worth it for the peace of mind and comfort I got. Also, I made sure the product was readily available online or at local stores to avoid running out unexpectedly.
My Final Tips
- Always follow the instructions carefully to avoid damaging your lenses or irritating your eyes.
- Don’t skip enzyme cleaning—protein buildup can cause discomfort and blurry vision.
- Consult your eye care professional if you’re unsure which cleaner suits your lenses best.
By paying attention to these factors, I was able to find a contact lens enzyme cleaner that worked well for me and kept my eyes healthy and comfortable every day.
Author Profile

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I’m Juan Dayton, the voice behind spicerarnold.com. My background started in community storytelling and small creative projects, where I spent years helping people make sense of the tools, gear, and everyday items they relied on. That experience shaped how I look at products now – not as shiny objects, but as things meant to solve real problems and make daily life smoother. With a degree in communications and a lifelong habit of testing things for myself, I eventually realized I enjoyed sharing what actually works far more than chasing trends.
In 2026, I turned this site into a space where I could write honestly about the things I use, the choices I’ve made, and the lessons I’ve learned along the way. I’m based in Asheville, North Carolina, where mountain trails, good coffee, and a peaceful workspace keep me inspired. Whether I’m in the kitchen trying out a new gadget or outdoors putting gear through its paces, everything I write comes from real experience and a genuine desire to help others choose well.
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